<p>Various factors, such as mental disorders, may affect the desire for medication and adherence to it in HIV/AIDS patients. The present study aimed to determine levels of neurotic disorders and relationships of levels of disorders and HAART medication adherence in HIV/ AIDS patients. To this end, 150 clients of Behavioral Disease Counseling Center of Shiraz were selected by a convenience method and were evaluated through Symptom Checklist-25 (SCL-25) and Medication Adherence Questionnaire (MAQ) in patients with chronic diseases. According to findings, 78% of patients had mental health, and 83% had very good medication adherence. It was also proven that being female, single or divorced, and working in temporary and low-income jobs reduced mental health levels. Age and higher education, on the other hand, led to greater adherence. According to the combination of the two findings, almost all psychological items could affect the medication adherence. Therefore, psychological treatment is in the top priority in the case of mental disorders in HIV/ AIDS patients; and also the anxiety was in the top priority among mental disorders.</p>
<p><strong>Keywords</strong>: Medication adherence; mental disorders; mental state; HIV/AIDS; Antiretroviral therapy (ART)</p>