<p>A model of structural equations was developed with the aim of recognizing which factors of the historical-sociocultural premises, individualism-collectivism and family functioning predict the moral domain in Mexican adolescents. The data were collected in a sample of 459 adolescent residents of Mexico City and the State of Mexico. The results show that the traditional norms of Mexican culture, collectivism and the family functioning, both in its positive and negative components, predict the moral domain divided into prescriptive moral principles and restrictive moral principles. The evidence obtained in this research suggests that for promoting a sensitive moral education to adolescents’ mental health, this moral education must promote sociocultural aspects that complement individual aspects.</p>