<p><strong><span style="vertical-align: inherit;"><span style="vertical-align: inherit;">Antecedentes: el</span></span></strong><span style="vertical-align: inherit;"><span style="vertical-align: inherit;"> confinamiento ha sido la estrategia más eficaz para mitigar el número de infecciones del virus SARS-COV-2. </span><span style="vertical-align: inherit;">Sin embargo, estar en aislamiento también trae consecuencias de otro orden, por ejemplo, a nivel psicosocial, que pueden estar asociadas a suplir necesidades básicas, posibilidades de conflicto, desesperanza, soledad, y por supuesto, enfrentar cambios en las rutinas y la incertidumbre que esta genera.</span></span></p>
<p><strong><span style="vertical-align: inherit;"><span style="vertical-align: inherit;">Objetivo:</span></span></strong><span style="vertical-align: inherit;"><span style="vertical-align: inherit;"> Identificar el impacto del confinamiento por SARS-COV-2 en la calidad de vida psicológica y social.</span></span></p>
<p><strong>Method:</strong> Cross-sectional study, where the application of the GHQ12 General Health Questionnaire was carried out in Colombian adults between April and July 2020 through a virtual form on the Google docs platform. Statistical analysis was performed with the Microsoft 365 Excel program (Microsoft corporation, 2007) by means of differential weighting per item according to Likert scale items.</p>
<p><strong>Results:</strong> 1035 Colombian adults who were in preventive isolation during the SARS-COV-2 quarantine, which in general were affected in aspects such as: concentration, sleep, enjoyment of activities among others, with a high self-esteem mismatch.</p>
<p><strong>Conclusions:</strong> The confinement by SARS-COV-2 appeared as an unexpected situation generating a significant impact on the mental health on the Colombian population.</p>