<p>Sexually transmitted infections are a public health problem. For this reason, the objective of this research was to determine the effectiveness of the professional biographical intervention program with cognitive behavioral techniques to decrease sexual risk behaviors in men who have sex with men (MSM). A quasi-experimental design with pre-test and post-test of two blocks was applied. In the experimental group, the first block was made up of 9 MSM with some sexually transmitted infection (STI), and the second block was made up of 11 MSM without any STI; in the control group, 8 and 11 MSM belonged to the first and second block, respectively. Participants responded to a scale whose validity and reliability are reported. The results show differences between the pre-test and post-test of the experimental and control groups, in both blocks, with a large effect size; also, differences between the pre-test and post-test of the experimental groups, while the control groups obtained no variation. In conclusion, the program reduces sexual risk behaviors in MSM.&nbsp; However, in those with STIs, the behaviors decreased, without disappearing. Finally, it contributes with an intervention proposal aimed at a high-risk population, whose contributions and limitations are discussed.</p>
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