<p><strong>Background: </strong>The objective of this study was to analyze the psychometric properties of the ORTO-15 questionnaire, for the Mexican population in university students. This questionnaire was designed to assess the presence of orthorexia nervosa (ON).</p>
<p><strong>Method: </strong>The sample consisted of 911 Mexican university students (65.4% women) aged between 18 and 28 years (M = 21 ± 1.9) who answered the Spanish version of the ORTO-15.</p>
<p><strong>Results: </strong>The results of the factor analysis with a varimax rotation yielded a structure of 14 test items made up of four factors, which explained 52.4% of the variance. Likewise, an adequate internal consistency was obtained (Cronbach's alpha = 0.78).</p>
<p><strong>Conclusion: </strong>The psychometric properties of the Spanish version of the ORTO-15 are supported as a reliable tool for the evaluation of nervous orthorexia in the Mexican population; however, it is important to consider the influence of the Mexican culture. Its use is expected to contribute significantly to a better understanding of the impact this behavior has on the Mexican population.</p>