<p>The objective of this investigation was to assessment the quality of life and academic procrastination among college students during the quarantine by Covid-19 and to identify the influence of access to technology and substance use as factors associated to better quality of life and less presence of academic procrastination. The World Health Organization WHOQOL-BREF and EPA was used to measure that variables as well as a questionnaire of questionnaire of sociodemographic data to know aspects related to access to resources technology and substance use. Correlations between most of procrastination and quality of life factors were found, except with social relationships and environment. Differences by sex were found only in the physical factor; Internet access influenced academic self-regulation and the environment factor; the access to own computer in the physical, social relations and environment but not in psychological factor; no differences were found by type of university. Differences by frequency of physical activity in the academic self-regulation factor; and by frequency and cigarette consumption in the academic self-regulation, procrastination, and psychological factors. &nbsp;</p>