<p>The purpose of this research was to describe the responses of students to confinement by Covid-19 and how their lives have changed in the face of this disease. The sample was 4414 university students; a descriptive and cross-sectional method was used in which the participants answered a survey in April 2020, at the beginning of the confinement. The results show a high perception of risk for the general population and the severity of the consequences, they feel informed, take preventive measures and perceive a low perceived probability of being infected. Confinement has interfered with classes, their learning, they feel isolation, it has affected them economically, they show more concern for their family and greater vulnerability is observed when belonging to an ethnic group. Significant associations are explored and results are discussed with theory.</p>