<p><strong>Objective</strong>: to identify the accumulated knowledge about men who have sex with men (MSM), 2010-2019. <strong>Methodology</strong>: a systematic review was carried out, using an autochthonous instrument, which included: Main topics covered; Population of interest; Types of studies and area of ​​knowledge. 51 texts were obtained from: DIALNET, EBSCO, REDALYC and SCIENCEDIRECT, official texts and / or recommended by experts. <strong>Results</strong>: the topics most addressed were: sexual practices, sexuality, HIV / AIDS, rights and volence. The social sciences present the highest academic productivity, followed by the medical sciences. <strong>Conclusions</strong>: the MSM population has a higher risk of suicide, drug addiction and HIV, the risk increases due to lack of affiliation to the social security system, immigration status, lack of social, family and institutional support networks, discrimination and negligence in public policies.</p>