<p>The objective of this study was to describe the causes and symptoms of discomfort in Colombian housewives, as well as the defense strategies they use to intervene in their own discomfort. For this purpose, the concepts of discomfort and defense strategies based on the psychodynamics and work clinics were described as those that affect the daily work of the subjects in their work and private context. The method was based on a qualitative case study, in which a semi-structured interview applied to seven Colombian housewives was used. Regarding the results, it was evidenced that the main causes of discomfort are the restrictions imposed by the current rulers, as well as the compulsory acquisition of adaptive skills for the new normal. Physical symptoms were found, such as pain in various parts of the body, and psychological symptoms, such as anxiety and lack of motivation. Finally, various defense strategies are evidenced, such as the verbalization of discomfort, family support and self-care.</p>