<p>The aim of this study was to assess personality, self-efficacy and depression factors in chronic renal patients awaiting kidney transplant. Patients (<em>n</em> = 65) were adults under hemodialysis treatment and on the kidney transplant list with average age of 49.11 years. Pearson correlation analysis showed positive associations between the factors Surgency (<em>r</em>=-.353, <em>p</em>&lt;.01) Conscientiousness (<em>r</em>=.415, <em>p</em>&lt;.01) and self-efficacy; Neuroticism had negative correlation with self-efficacy (<em>r</em>=-.389, <em>p</em>&lt;.01) and total (<em>r</em>=.688, <em>p</em>&lt;0.01), psychological (<em>r</em>=.627, <em>p</em>&lt;0.01) and somatic (<em>r</em>=.673, <em>p</em>&lt;.01) depression levels; and the factors Conscientiousness and Agreableness also correlated positively and significantly with age (<em>r</em>=.381, <em>p</em>&lt;.01; <em>r</em>=.309, <em>p</em>&lt;.05 respectively) and age at diagnosis (<em>r</em>=.450, <em>p</em>&lt;.05; <em>r</em>=0.271, <em>p</em>&lt;.01). Neuroticism was significantly a predictor (<em>R<sup>2</sup></em>= .47, β=5.35, p&lt;.01) of depressive symptoms, while Conscientiousness, Neuroticism and Surgency factors together  were predictors of self-efficacy in these patients (<em>R<sup>2</sup></em>= .33, β=.23, <em>p</em>&lt;.05). Personality factors must be considered in patients on the kidney transplant list, because they impact on behavior and depression levels of these patients.</p>