<p>Gender-based violence has serious consequences for women's health and its effects are aggravated when abuse has occurred throughout the life cycle. In addition, it can develop in the victims feelings of guilt that negatively influence their mental health. The sample consists of 129 victims of gender violence in Nicaragua, a group that has suffered from different forms of poly-victimization since childhood. The development of feelings of guilt is associated with the history of abuse and influences the health of the victims, who present higher levels of anxiety and depression than those who do not feel guilty. Knowing the problem allows its consideration in the treatment and intervention processes with those who have suffered gender violence.</p>